apalutamide will lower the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with drugs which are CYP3A4 substrates can result in reduced exposure to those medications.As usually, having said that, often take into accou… Read More

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